Somatostatin receptor · PROTEIN FAMILY · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P30680. Use UniProt P30680 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30680 as the stable identity anchor, then attach disease evidence before program review.
Somatostatin receptor type 2
Review this target as Somatostatin receptor, mapped to UniProt P30680. ChEMBL maps the protein component as Somatostatin receptor type 2. Sequence length is 369 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Somatostatin receptor as ChEMBL target CHEMBL2096977, mapped to UniProt P30680. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Somatostatin receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | P30680 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Somatostatin receptor type 2 |
| UniProt Accession | P30680 |
| Component Type | Protein |
| Sequence Length | 369 aa |
Somatostatin receptor type 2
Review this target as Somatostatin receptor, mapped to UniProt P30680. ChEMBL maps the protein component as Somatostatin receptor type 2. Sequence length is 369 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL373632 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL1823872 | 9.7 | IC50 | 0.2 | Clinical |
| CHEMBL222751 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL265525 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL415495 | 9.37 | IC50 | 0.43 | Preclinical |
| CHEMBL2311098 | 9.28 | IC50 | 0.53 | Preclinical |
| CHEMBL263620 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL374316 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL2369755 | 9.14 | IC50 | 0.73 | Preclinical |
| CHEMBL439106 | 8.96 | IC50 | 1.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 34 | 6.4 |
| cell membrane format | 5 | 9 | 7.1 |
| tissue-based format | 2 | 8 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 50 | 7.5 |
| assay format | 2 | 26 | 6.4 |