Compound Detail
CHEMBL374316
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CCS)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O
Basic Information
| ChEMBL ID | CHEMBL374316 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | XTUCWHMNPIHPRQ-LFSOJSGESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
855.1
MW (Da)
2.27
ALogP
9
HBA
9
HBD
227.8
PSA (Ų)
0.07
QED
2
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor CHEMBL2096977 | IC50 | 9.15 | 9.15 | 0.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor | IC50 | = | 0.7 | nM | 9.15 | Displacement of [125I]SRIF-14 from SSTR of rat AR42J cell membranes | 17315859 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17315859 | 10.1021/jm061290i | Somatostatin receptor | 1 |
Data from ChEMBL 36 via Core Engine