Compound Detail
CHEMBL443660
CALYCULIN D Enter ChEMBL ID:
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COC[C@@H]([C@H](O)[C@H](O)C(=O)N[C@H](C)C[C@H](C)c1nc(/C=C/C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C(C)=C/C=C/C(C)=C/C#N)OC)[C@H](OP(=O)(O)O)C3(C)C)co1)N(C)C
Basic Information
| ChEMBL ID | CHEMBL443660 |
| Name | CALYCULIN D |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MDHVPFKPZGGNLB-CRRDXKEOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1023.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 9.05 | 9.05 | 0.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 0.9 | nM | 9.05 | Inhibition of protein phosphatase 2A | 1812209 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1812209 | 10.1021/np50078a001 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine