Compound Detail
CHEMBL4439201
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O=C(O)C1=CC(C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O
Basic Information
| ChEMBL ID | CHEMBL4439201 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YETAHXYTPZCNBG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
424.4
MW (Da)
2.39
ALogP
6
HBA
5
HBD
169.4
PSA (Ų)
0.44
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein argonaute-2 CHEMBL4680043 | IC50 | 6.35 | 6.35 | 450.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein argonaute-2 | IC50 | = | 450.0 | nM | 6.35 | Inhibition of AGO2 (unknown origin) | 31931338 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31931338 | 10.1016/j.ejmech.2019.112008 | Protein argonaute-2 | 1 |
Data from ChEMBL 36 via Core Engine