Protein argonaute-2 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q9UKV8. Use UniProt Q9UKV8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UKV8 as the stable identity anchor, then attach disease evidence before program review.
Protein argonaute-2
Review this target as Protein argonaute-2, mapped to UniProt Q9UKV8. Sequence length is 859 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein argonaute-2 as ChEMBL target CHEMBL4680043, mapped to UniProt Q9UKV8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein argonaute-2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UKV8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein argonaute-2 |
| UniProt Accession | Q9UKV8 |
| Component Type | Protein |
| Sequence Length | 859 aa |
Protein argonaute-2
Review this target as Protein argonaute-2, mapped to UniProt Q9UKV8. Sequence length is 859 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4439201 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL265502 | 6.16 | IC50 | 690.0 | Clinical |
| CHEMBL451197 | 5.79 | IC50 | 1610.0 | Preclinical |
| CHEMBL485696 | 5.37 | Kd | 4300.0 | Approved |
| CHEMBL214393 | 4.82 | Kd | 15000.0 | Preclinical |
| CHEMBL21 | 4.77 | Kd | 17000.0 | Approved |
| CHEMBL338802 | 4.31 | Kd | 49000.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 8 | 5.4 |