Compound Detail
CHEMBL4446279
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Basic Information
| ChEMBL ID | CHEMBL4446279 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LJLGLQXLFHTQCG-MDWZMJQESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
385.4
MW (Da)
5.72
ALogP
5
HBA
0
HBD
65.5
PSA (Ų)
0.30
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.45
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | EC50 | 4.45 | 4.45 | 35600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | EC50 | = | 35600.0 | nM | 4.45 | Activation of mushroom tyrosinase using L-tyrosine as substrate preincubated for... | 27622747 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27622747 | 10.1016/j.bmc.2016.08.066 | B16-F10 | 1 |
| 27622747 | 10.1016/j.bmc.2016.08.066 | Tyrosinase | 1 |
Data from ChEMBL 36 via Core Engine