Compound Detail
CHEMBL4453191
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Basic Information
| ChEMBL ID | CHEMBL4453191 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKTZTLJVZHRMME-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
350.3
MW (Da)
3.93
ALogP
4
HBA
1
HBD
59.3
PSA (Ų)
0.61
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nuclear receptor subfamily 4 group A member 2 CHEMBL3879839 | EC50 | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nuclear receptor subfamily 4 group A member 2 | EC50 | = | 1.0 | nM | 9.0 | Agonist activity at Nurr1 in mouse N2A cells harboring NBRE by luciferase report... | 30773432 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30773432 | 10.1016/j.bmcl.2019.01.024 | Nuclear receptor subfamily 4 group A member 2 | 4 |
Data from ChEMBL 36 via Core Engine