Compound Detail
CHEMBL445402
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Basic Information
| ChEMBL ID | CHEMBL445402 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YACHJFKLNKAWJL-VVUWUOFOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
382.5
MW (Da)
-0.68
ALogP
8
HBA
5
HBD
138.0
PSA (Ų)
0.32
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 4.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ribosomal RNA A-site CHEMBL614640 | Kd | 4.57 | 4.57 | 27000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ribosomal RNA A-site | Kd | = | 27000.0 | nM | 4.57 | Dissociation constant against 16S rRNA A-site | 16168642 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16168642 | 10.1016/j.bmcl.2005.08.027 | Ribosomal RNA A-site | 1 |
| 16168642 | 10.1016/j.bmcl.2005.08.027 | Nucleic Acid | 1 |
Data from ChEMBL 36 via Core Engine