Compound Detail
CHEMBL445661
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Basic Information
| ChEMBL ID | CHEMBL445661 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LGQASALZGMUVJX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
263.3
MW (Da)
4.04
ALogP
2
HBA
1
HBD
25.2
PSA (Ų)
0.65
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL3072 | IC50 | 6.04 | 6.04 | 920.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | IC50 | = | 920.0 | nM | 6.04 | Inhibition of rat AR-mediated reporter gene expression in COS7 cells | 16603353 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16603353 | 10.1016/j.bmcl.2006.03.047 | Androgen receptor | 1 |
Data from ChEMBL 36 via Core Engine