Compound Detail
CHEMBL4475816
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Basic Information
| ChEMBL ID | CHEMBL4475816 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AQKVBCXAXBLUOR-IRXDYDNUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
380.5
MW (Da)
2.25
ALogP
6
HBA
0
HBD
66.9
PSA (Ų)
0.53
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Feline immunodeficiency virus CHEMBL613744 | EC50 | 6.8 | 6.8 | 160.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Feline immunodeficiency virus | EC50 | = | 160.0 | nM | 6.8 | Antiviral activity against FIV infected in cat FL-4 cells assessed as reduction ... | 31395510 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31395510 | 10.1016/j.bmc.2019.07.047 | Unchecked | 2 |
| 31395510 | 10.1016/j.bmc.2019.07.047 | Feline immunodeficiency virus | 1 |
| 31395510 | 10.1016/j.bmc.2019.07.047 | ADMET | 1 |
| 31395510 | 10.1016/j.bmc.2019.07.047 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine