Compound Detail
CHEMBL449890
MANSONONE A Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL449890 |
| Name | MANSONONE A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DXGOWNAYXJKDFJ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
232.3
MW (Da)
3.08
ALogP
2
HBA
0
HBD
34.1
PSA (Ų)
0.51
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leptomonas seymouri CHEMBL612917 | IC50 | 5.07 | 5.07 | 8500.0 | 1 |
| Crithidia fasciculata CHEMBL612650 | IC50 | 4.82 | 4.82 | 15000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leptomonas seymouri | IC50 | = | 8500.0 | nM | 5.07 | Antitrypanosomal activity against Leptomonas seymouri | 18276039 |
| Crithidia fasciculata | IC50 | = | 15000.0 | nM | 4.82 | Antitrypanosomal activity against Crithidia fasciculata | 18276039 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18276039 | 10.1016/j.ejmech.2007.12.023 | No relevant target | 2 |
| 18276039 | 10.1016/j.ejmech.2007.12.023 | Leptomonas seymouri | 1 |
| 18276039 | 10.1016/j.ejmech.2007.12.023 | Crithidia fasciculata | 1 |
Data from ChEMBL 36 via Core Engine