Compound Detail
CHEMBL4518711
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4518711 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTSWUTVZEJOAKU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
457.1
MW (Da)
3.67
ALogP
5
HBA
4
HBD
123.9
PSA (Ų)
0.52
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.79
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| WD repeat-containing protein 5 CHEMBL1075317 | Kd | 6.79 | 6.79 | 163.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| WD repeat-containing protein 5 | Kd | = | 163.0 | nM | 6.79 | Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged... | 31724864 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31724864 | 10.1021/acs.jmedchem.9b01411 | WD repeat-containing protein 5 | 2 |
Data from ChEMBL 36 via Core Engine