Compound Detail
CHEMBL4521304
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Basic Information
| ChEMBL ID | CHEMBL4521304 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZRGMAZKCCJMDJW-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
421.9
MW (Da)
1.24
ALogP
8
HBA
1
HBD
116.0
PSA (Ų)
0.68
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fascin CHEMBL4523304 | IC50 | 5.37 | 5.37 | 4300.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fascin | IC50 | = | 4300.0 | nM | 5.37 | Inhibition of GST-tagged recombinant human fascin 1 expressed in Escherichia col... | - |
| Fascin | IC50 | = | 4300.0 | nM | 5.37 | Chemical Library Screens and Analysis: About 150,000 compounds were screened. Th... | - |
Data from ChEMBL 36 via Core Engine