Compound Detail
CHEMBL4526803
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Basic Information
| ChEMBL ID | CHEMBL4526803 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QHCHXNVQIFBGRR-JYRVWZFOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
195.2
MW (Da)
2.55
ALogP
1
HBA
0
HBD
26.1
PSA (Ų)
0.29
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Retinoid isomerohydrolase CHEMBL4523306 | IC50 | 4.22 | 4.22 | 60000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Retinoid isomerohydrolase | IC50 | = | 60000.0 | nM | 4.22 | Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in isomero-hy... | - |
Data from ChEMBL 36 via Core Engine