Compound Detail
CHEMBL4537201
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4537201 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LVYURVZCXFWMGP-VKAVYKQESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
453.5
MW (Da)
6.04
ALogP
4
HBA
1
HBD
64.1
PSA (Ų)
0.51
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL2243 | IC50 | 6.29 | 6.29 | 508.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 508.0 | nM | 6.29 | Inhibition of human transmembrane domain deficient FFAH expressed in Escherichia... | 30503633 |
| Fatty-acid amide hydrolase 1 | IC50 | = | 508.0 | nM | 6.29 | FAAH Assay: All reagents were purchased from Sigma-Aldrich unless specified. Hum... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30503633 | 10.1016/j.bmcl.2018.11.048 | Fatty-acid amide hydrolase 1 | 2 |
Data from ChEMBL 36 via Core Engine