Compound Detail
CHEMBL453867
PSICOFURANINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL453867 |
| Name | PSICOFURANINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BNZYRKVSCLSXSJ-IOSLPCCCSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
297.3
MW (Da)
-2.83
ALogP
10
HBA
5
HBD
159.8
PSA (Ų)
0.40
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GMP synthase [glutamine-hydrolyzing] CHEMBL5721 | IC50 | 4.76 | 4.76 | 17300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GMP synthase [glutamine-hydrolyzing] | IC50 | = | 17300.0 | nM | 4.76 | Inhibition of human GMP synthase | 30964283 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30964283 | 10.1021/acs.jmedchem.9b00182 | GMP synthase [glutamine-hydrolyzing] | 2 |
| 18834112 | 10.1021/jm800656v | Amine oxidase [flavin-containing] A | 1 |
| 30964283 | 10.1021/acs.jmedchem.9b00182 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine