Compound Detail
CHEMBL4583201
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Basic Information
| ChEMBL ID | CHEMBL4583201 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UFMQRARCXUCJDI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
452.2
MW (Da)
4.26
ALogP
4
HBA
3
HBD
86.6
PSA (Ų)
0.61
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| WD repeat-containing protein 5 CHEMBL1075317 | Kd | 6.26 | 6.26 | 547.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| WD repeat-containing protein 5 | Kd | = | 547.0 | nM | 6.26 | Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged... | 31724864 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31724864 | 10.1021/acs.jmedchem.9b01411 | WD repeat-containing protein 5 | 1 |
Data from ChEMBL 36 via Core Engine