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Compound Detail

CHEMBL4594338

NEDOSIRAN SODIUM
💊 Approved Drug
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💊 Approved Drug
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ChEMBL ↗

Basic Information

ChEMBL ID CHEMBL4594338
Name NEDOSIRAN SODIUM
Phase Approved
Structure Type NONE
Therapeutic ✓ Yes

Known Names

Dcr-phxc Nedosiran sodium Rivfloza
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
3
Known Names
2
Indications
1
Mechanisms

Drug Information

Molecule Type Oligonucleotide
First Approval 2023
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

First in Class
USAN Year 2019

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
L-lactate dehydrogenase A chain mRNA RNAi inhibitor RNAI INHIBITOR L-lactate dehydrogenase A chain mRNA ✓ ✓

Indications

Hyperoxaluria, Primary Hyperoxaluria, Primary

Data from ChEMBL 36 via Core Engine