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Compound Detail

CHEMBL4594379

FOSLEVODOPA
💊 Approved Drug
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💊 Approved Drug
N[C@@H](Cc1ccc(OP(=O)(O)O)c(O)c1)C(=O)O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4594379
Name FOSLEVODOPA
Phase Approved
Structure Type MOL
InChI Key YNDMEEULGSTYJT-LURJTMIESA-N
Active Moiety CHEMBL59

Known Names

3-hydroxy-o-phosphono-l-tyrosine ABBV-951 Foslevodopa FOSLEVODOPA COMPONENT OF ABBV-951 Foslevodopa component of vyalev Levodopa-4'-monophosphate
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
6
Known Names
1
Indications
1
Mechanisms

Molecular Properties

277.2
MW (Da)
-0.18
ALogP
5
HBA
5
HBD
150.3
PSA (Ų)
0.46
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
First Approval 2024
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

Prodrug
USAN Stem -dopa; fos-
USAN Year 2020

Extended Properties

Molecular Formula C9H12NO7P
MW 277.17
Aromatic Rings 1
Heavy Atoms 18
NP-Likeness 1.20

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Beta-1 adrenergic receptor agonist AGONIST Beta-1 adrenergic receptor ✓ ✓

Indications

Parkinson Disease

Data from ChEMBL 36 via Core Engine