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Compound Detail

CHEMBL4594503

TALQUETAMAB
💊 Approved Drug
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💊 Approved Drug
No structure available
ChEMBL ↗

Basic Information

ChEMBL ID CHEMBL4594503
Name TALQUETAMAB
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

JNJ-63483043 JNJ-64407564 Talquetamab Talquetamab-tgvs Talvey
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
5
Known Names
3
Indications
2
Mechanisms

Drug Information

Molecule Type Antibody
First Approval 2023
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

Black Box Warning First in Class
USAN Stem -mab
USAN Year 2021

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
T cell surface glycoprotein CD3 binding agent BINDING AGENT T cell surface glycoprotein CD3 ✓ ✓
G-protein coupled receptor family C group 5 member D binding agent BINDING AGENT G-protein coupled receptor family C group 5 member D ✓ ✓

Indications

Multiple Myeloma Neoplasms Hematologic Diseases

ATC Classification

L01FX29
talquetamab
Level 1: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Level 2: ANTINEOPLASTIC AGENTS

Drug Warnings

Black Box Warning
immune system toxicity
Country: United States

Data from ChEMBL 36 via Core Engine