Compound Detail
CHEMBL461024
CARCININE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL461024 |
| Name | CARCININE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ANRUJJLGVODXIK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
182.2
MW (Da)
-0.58
ALogP
3
HBA
3
HBD
83.8
PSA (Ų)
0.57
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL4124 | Ki | 6.53 | 6.53 | 294.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 294.0 | nM | 6.53 | Displacement of [3H]NAMH from rat full length histamine H3 receptor expressed in... | 18683917 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28535470 | 10.1016/j.ejmech.2017.05.034 | IL15-IL15 receptor | 2 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| 18683917 | 10.1021/jm8003625 | Histamine H3 receptor | 1 |
| 28535470 | 10.1016/j.ejmech.2017.05.034 | PBMC | 1 |
Data from ChEMBL 36 via Core Engine