Compound Detail
CHEMBL4635871
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4635871 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ANWLFOLYHZHQIN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
235.2
MW (Da)
2.29
ALogP
4
HBA
0
HBD
61.0
PSA (Ų)
0.61
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 2.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Son of sevenless homolog 1 CHEMBL2079846 | Kd | 2.92 | 2.92 | 1200000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Son of sevenless homolog 1 | Kd | = | 1200000.0 | nM | 2.92 | Binding affinity to IVLM methyl-labeled SOS1 catalytic domain (566 to 1046 resid... | 32673492 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32673492 | 10.1021/acs.jmedchem.0c00511 | Son of sevenless homolog 1 | 1 |
Data from ChEMBL 36 via Core Engine