Compound Detail
CHEMBL4637295
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Basic Information
| ChEMBL ID | CHEMBL4637295 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LMOLVAMZQBFMFZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
313.9
MW (Da)
4.81
ALogP
1
HBA
1
HBD
12.0
PSA (Ų)
0.62
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2B CHEMBL1904 | Ki | 8.68 | 8.68 | 2.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2B | Ki | = | 2.1 | nM | 8.68 | Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse ... | 31843460 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31843460 | 10.1016/j.bmc.2019.115245 | Glutamate receptor ionotropic, NMDA 2B | 1 |
Data from ChEMBL 36 via Core Engine