Compound Detail
CHEMBL4637732
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Basic Information
| ChEMBL ID | CHEMBL4637732 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YUDMINLWCYBJCT-BJMVGYQFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
398.4
MW (Da)
4.71
ALogP
4
HBA
0
HBD
76.6
PSA (Ų)
0.33
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 8.99
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Alpha-synuclein CHEMBL6152 | Kd | 8.99 | 8.99 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Alpha-synuclein | Kd | = | 1.03 | nM | 8.99 | Binding affinity to human wlid-type alpha-synuclein by SPR analysis | 32081628 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32081628 | 10.1016/j.bmc.2020.115358 | Alpha-synuclein | 2 |
Data from ChEMBL 36 via Core Engine