Compound Detail
CHEMBL4638578
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Basic Information
| ChEMBL ID | CHEMBL4638578 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MPCOIYCMHATPAS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
354.8
MW (Da)
2.92
ALogP
5
HBA
2
HBD
79.8
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | Ki | 7.77 | 7.77 | 16.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 | Ki | = | 16.9 | nM | 7.77 | Antagonist activity at 5-HT6 receptor (unknown origin) | 30496988 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30496988 | 10.1016/j.ejmech.2018.11.017 | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine