Compound Detail
CHEMBL4639665
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Basic Information
| ChEMBL ID | CHEMBL4639665 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PICSGDJZUKVMGU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
455.2
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein kinase BTK CHEMBL5251 | IC50 | 6.57 | 6.57 | 267.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase BTK | IC50 | = | 267.8 | nM | 6.57 | Inhibition of recombinant human His-tagged full length BTK expressed in baculovi... | 31843459 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31843459 | 10.1016/j.bmc.2019.115236 | Tyrosine-protein kinase BTK | 1 |
Data from ChEMBL 36 via Core Engine