Compound Detail
CHEMBL4642037
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Basic Information
| ChEMBL ID | CHEMBL4642037 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | TXCUANMKBQKTCW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
426.0
MW (Da)
3.84
ALogP
5
HBA
0
HBD
36.8
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.69
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 6.69 | 6.69 | 203.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 203.0 | nM | 6.69 | Antiviral activity against HCV J6/JFH/JC1 infected in human Huh7.5 cells incubat... | 32378892 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32378892 | 10.1021/acs.jmedchem.0c00232 | Unchecked | 2 |
| 32378892 | 10.1021/acs.jmedchem.0c00232 | Hepatitis C virus | 1 |
Data from ChEMBL 36 via Core Engine