Compound Detail
CHEMBL4648654
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Basic Information
| ChEMBL ID | CHEMBL4648654 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VPYKDTQNFGAIKE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
467.6
MW (Da)
5.65
ALogP
5
HBA
0
HBD
19.4
PSA (Ų)
0.46
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human orthopneumovirus CHEMBL613127 | EC50 | 5.48 | 5.48 | 3310.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human orthopneumovirus | EC50 | = | 3310.0 | nM | 5.48 | Antiviral activity against Respiratory syncytial virus A strain Long infected in... | 32143992 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32143992 | 10.1016/j.bmc.2020.115401 | Human orthopneumovirus | 1 |
| 32143992 | 10.1016/j.bmc.2020.115401 | HEp-2 | 1 |
Data from ChEMBL 36 via Core Engine