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Compound Detail

CHEMBL4650393

EPCORITAMAB
💊 Approved Drug
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💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL4650393
Name EPCORITAMAB
Phase Approved
Structure Type SEQ
Therapeutic ✓ Yes

Known Names

Epcoritamab Epcoritamab-bysp Epkinly GEN-3013 GEN3013 Tepkinly
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
6
Known Names
8
Indications
2
Mechanisms

Drug Information

Molecule Type Antibody
First Approval 2023
Availability Prescription
Chirality Single Enantiomer

Routes of Administration

Parenteral

Flags

Black Box Warning
USAN Stem -mab
USAN Year 2022

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
B-lymphocyte antigen CD20 binding agent BINDING AGENT B-lymphocyte antigen CD20
T cell surface glycoprotein CD3 binding agent BINDING AGENT T cell surface glycoprotein CD3

Indications

Lymphoma, Follicular Lymphoma, Follicular Lymphoma, Large B-Cell, Diffuse Neoplasms Lymphoma, Non-Hodgkin Leukemia, Lymphocytic, Chronic, B-Cell Lymphoma, B-Cell Lymphoma, Mantle-Cell

ATC Classification

L01FX27
epcoritamab
Level 1: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Level 2: ANTINEOPLASTIC AGENTS

Drug Warnings

Black Box Warning
immune system toxicity
Country: United States

Data from ChEMBL 36 via Core Engine