Compound Detail
CHEMBL467560
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL467560 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OSHPCEQPUKKIAZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
351.4
MW (Da)
5.23
ALogP
4
HBA
0
HBD
39.4
PSA (Ų)
0.45
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bone morphogenetic protein 4 CHEMBL5350 | IC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bone morphogenetic protein 4 | IC50 | = | 150.0 | nM | 6.82 | Inhibition of BMP4-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular EL... | 18621530 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18621530 | 10.1016/j.bmcl.2008.06.052 | Bone morphogenetic protein 4 | 1 |
Data from ChEMBL 36 via Core Engine