Compound Detail
CHEMBL467724
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Basic Information
| ChEMBL ID | CHEMBL467724 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SJLBTVPFEBWSGX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
338.4
MW (Da)
1.87
ALogP
5
HBA
3
HBD
133.3
PSA (Ų)
0.49
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acid-sensing ion channel 3 CHEMBL5368 | IC50 | 6.19 | 6.19 | 640.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acid-sensing ion channel 3 | IC50 | = | 640.0 | nM | 6.19 | Inhibition of ASIC3 assessed as inhibition of peak current by patch clamp electr... | 19339181 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19339181 | 10.1016/j.bmcl.2009.03.029 | Acid-sensing ion channel 3 | 3 |
Data from ChEMBL 36 via Core Engine