Compound Detail
CHEMBL471331
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Basic Information
| ChEMBL ID | CHEMBL471331 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MVIRVXIGHRLVRN-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
348.7
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin G/H synthase 1 CHEMBL2860 | IC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase 1 | IC50 | = | 10.0 | nM | 8.0 | Inhibition of bovine COX1 | 17976864 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17976864 | 10.1016/j.ejmech.2007.09.007 | Prostaglandin G/H synthase 1 | 1 |
| 17976864 | 10.1016/j.ejmech.2007.09.007 | NON-PROTEIN TARGET | 1 |
| 17976864 | 10.1016/j.ejmech.2007.09.007 | Prostaglandin G/H synthase 2 | 1 |
| 17976864 | 10.1016/j.ejmech.2007.09.007 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine