Prostaglandin G/H synthase 1 · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt O62664. Use UniProt O62664 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O62664 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin G/H synthase 1
Review this target as Prostaglandin G/H synthase 1, mapped to UniProt O62664. Sequence length is 600 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin G/H synthase 1 as ChEMBL target CHEMBL2860, mapped to UniProt O62664. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin G/H synthase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | O62664 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin G/H synthase 1 |
| UniProt Accession | O62664 |
| Component Type | Protein |
| Sequence Length | 600 aa |
Prostaglandin G/H synthase 1
Review this target as Prostaglandin G/H synthase 1, mapped to UniProt O62664. Sequence length is 600 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL490292 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL139 | 8.52 | IC50 | 3.0 | Approved |
| CHEMBL473946 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL6 | 8.39 | IC50 | 4.1 | Approved |
| CHEMBL470304 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL522267 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL471331 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL514950 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL452730 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL471501 | 7.7 | IC50 | 20.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 19 | 41 | 5.5 |
| assay format | 5 | 30 | 6.3 |
| microsome format | 2 | 0 | — |
| tissue-based format | 1 | 5 | 4.7 |