Compound Detail
CHEMBL4745432
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Basic Information
| ChEMBL ID | CHEMBL4745432 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHMSZMJBEBIVGK-ZDUSSCGKSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
447.9
MW (Da)
1.31
ALogP
8
HBA
1
HBD
87.8
PSA (Ų)
0.63
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Probable G-protein coupled receptor 139 CHEMBL3632455 | EC50 | 9.0 | 9.0 | 1.0 | 1 |
| Probable G-protein coupled receptor 139 CHEMBL4888453 | EC50 | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Probable G-protein coupled receptor 139 | EC50 | = | 1.0 | nM | 9.0 | Agonist activity at human GPR139 expressed in CHO-K1 cells assessed as increase ... | - |
| Probable G-protein coupled receptor 139 | EC50 | = | 1.0 | nM | 9.0 | Agonist activity at rat GPR139 expressed in CHO-K1 cells assessed as increase in... | - |
Data from ChEMBL 36 via Core Engine