Compound Detail
CHEMBL4760545
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Basic Information
| ChEMBL ID | CHEMBL4760545 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IPRKBRUCDHXJNF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
403.5
MW (Da)
2.34
ALogP
7
HBA
1
HBD
80.1
PSA (Ų)
0.72
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | Ki | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 | Ki | = | 1.0 | nM | 9.0 | Displacement of [3H]-LSD from human 5HT6R expressed in HEK293 cell membranes inc... | 33439019 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33439019 | 10.1021/acs.jmedchem.0c02009 | Unchecked | 2 |
| 33439019 | 10.1021/acs.jmedchem.0c02009 | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine