Compound Detail
CHEMBL476099
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Basic Information
| ChEMBL ID | CHEMBL476099 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KBLLVDUPDMDMON-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
366.5
MW (Da)
4.33
ALogP
3
HBA
0
HBD
32.8
PSA (Ų)
0.71
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL264 | Ki | 8.4 | 8.4 | 4.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 4.0 | nM | 8.4 | Displacement of [3H]RAMH from human histamine H3 receptor expressed in CHO cells | 18606542 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18606542 | 10.1016/j.bmcl.2008.06.062 | Histamine H3 receptor | 1 |
Data from ChEMBL 36 via Core Engine