Compound Detail
CHEMBL4764695
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Basic Information
| ChEMBL ID | CHEMBL4764695 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WVBGRKCXHSEQHF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
308.4
MW (Da)
3.15
ALogP
6
HBA
1
HBD
63.3
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | Ki | 6.4 | 6.4 | 400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | Ki | = | 400.0 | nM | 6.4 | Inhibition of c-Met (unknown origin) using poly Glu-Tyr as substrate preincubate... | 34141080 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34141080 | 10.1021/acsmedchemlett.1c00094 | Hepatocyte growth factor receptor | 2 |
| 34141080 | 10.1021/acsmedchemlett.1c00094 | ADMET | 2 |
Data from ChEMBL 36 via Core Engine