Compound Detail
CHEMBL4765146
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)(C)c1cc(NC(=O)Nc2ccc3[nH]c(C(=O)c4cc5cc(O)ccc5[nH]4)cc3c2)no1
Basic Information
| ChEMBL ID | CHEMBL4765146 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WRAULJGFBJZOGI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
457.5
MW (Da)
5.52
ALogP
5
HBA
5
HBD
136.0
PSA (Ų)
0.23
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MV4-11 CHEMBL613835 | IC50 | 8.77 | 8.77 | 1.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MV4-11 | IC50 | = | 1.7 | nM | 8.77 | Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability ... | 32199135 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32199135 | 10.1016/j.ejmech.2020.112232 | MV4-11 | 1 |
Data from ChEMBL 36 via Core Engine