Compound Detail
CHEMBL477159
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Basic Information
| ChEMBL ID | CHEMBL477159 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ICNVEPWJOAKEMN-RRFJBIMHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
372.8
MW (Da)
2.79
ALogP
7
HBA
1
HBD
90.1
PSA (Ų)
0.55
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 4.82 | 4.82 | 15100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 15100.0 | nM | 4.82 | Antiviral activity against HCV assessed as inhibition of viral RNA replication i... | 18644724 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18644724 | 10.1016/j.bmcl.2008.07.015 | Hepatitis C virus | 1 |
| 18644724 | 10.1016/j.bmcl.2008.07.015 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine