Compound Detail
CHEMBL4789932
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Basic Information
| ChEMBL ID | CHEMBL4789932 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KAVCEJZYJAXPSY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
461.5
MW (Da)
4.89
ALogP
4
HBA
3
HBD
90.1
PSA (Ų)
0.45
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 CHEMBL4794 | EC50 | 8.55 | 8.55 | 2.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | EC50 | = | 2.79 | nM | 8.55 | Agonist activity at human TRPV1 expressed in CHO cells assessed as stimulation o... | 33385210 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33385210 | 10.1021/acs.jmedchem.0c00982 | Transient receptor potential cation channel subfamily V member 1 | 3 |
Data from ChEMBL 36 via Core Engine