Compound Detail
CHEMBL480216
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL480216 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FNMFHHBMZSWLCP-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
389.5
MW (Da)
4.13
ALogP
4
HBA
0
HBD
46.8
PSA (Ų)
0.63
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.3 | 5.95 | 501.2 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 501.19 | nM | 6.3 | Inhibition of H+/K+ ATPase in New Zealand rabbit gastric gland assessed as 14C]-... | 19026549 |
| Unchecked | IC50 | = | 2511.89 | nM | 5.6 | Inhibition of H+/K+ ATPase in hog gastric mucosa by malachite green assay | 19026549 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19026549 | 10.1016/j.bmc.2008.10.055 | Unchecked | 2 |
| 19026549 | 10.1016/j.bmc.2008.10.055 | No relevant target | 2 |
Data from ChEMBL 36 via Core Engine