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Compound Detail

CHEMBL4802263

CILTACABTAGENE AUTOLEUCEL
💊 Approved Drug
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💊 Approved Drug
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ChEMBL ↗

Basic Information

ChEMBL ID CHEMBL4802263
Name CILTACABTAGENE AUTOLEUCEL
Phase Approved
Structure Type NONE
Therapeutic ✓ Yes

Known Names

Carvykti Ciltacabtagene autoleucel JNJ-68284528 JNJ-68284528(LCAR-B38M CAR-T cells)
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
4
Known Names
1
Indications
1
Mechanisms

Drug Information

Molecule Type Gene
First Approval 2022
Availability Unknown
Chirality Single Enantiomer

Flags

Black Box Warning
USAN Year 2021

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Tumor necrosis factor receptor superfamily member 17 binding agent BINDING AGENT Tumor necrosis factor receptor superfamily member 17 ✓ ✓

Indications

Multiple Myeloma

ATC Classification

L01XL05
ciltacabtagene autoleucel
Level 1: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Level 2: ANTINEOPLASTIC AGENTS

Drug Warnings

Black Box Warning
musculoskeletal toxicity
Country: United States
Black Box Warning
hematological toxicity
Country: United States
Black Box Warning
hepatotoxicity
Country: United States

Data from ChEMBL 36 via Core Engine