Compound Detail
CHEMBL481111
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CCCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN(C)C[C@@H](O)c3ccco3)oc21
Basic Information
| ChEMBL ID | CHEMBL481111 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QXLVKFQRAODTIZ-JOCHJYFZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
498.0
MW (Da)
4.35
ALogP
7
HBA
2
HBD
100.8
PSA (Ų)
0.34
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.95
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.95 | 5.95 | 1120.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1120.0 | nM | 5.95 | Inhibition of HCMV DNA polymerase by scintillation proximity assay | 18595689 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18595689 | 10.1016/j.bmcl.2008.06.060 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine