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Compound Detail

CHEMBL482066

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CC(=O)c1c(O)cc(O)cc1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Basic Information

ChEMBL ID CHEMBL482066
Phase Preclinical
Structure Type MOL
InChI Key GFKQVLKFPJGJEP-LPUQOGTASA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

330.3
MW (Da)
-1.52
ALogP
9
HBA
6
HBD
156.9
PSA (Ų)
0.36
QED
1
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C14H18O9
MW 330.29
Aromatic Rings 1
Heavy Atoms 23
NP-Likeness 2.17

Activity Summary

Ki 1 meas. best 4.51

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Solute carrier family 28 member 3
CHEMBL5707
Ki 4.51 4.51 30770.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
19097778 10.1016/j.bmcl.2008.11.112 Solute carrier family 28 member 3 1

Data from ChEMBL 36 via Core Engine