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Target Snapshot

CHEMBL5707 Target Snapshot

Solute carrier family 28 member 3 · SINGLE PROTEIN · Homo sapiens

23Compounds
3Assays
2Approved Drugs
26.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q9HAS3. Use UniProt Q9HAS3 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9HAS3 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Solute carrier family 28 member 3 as ChEMBL target CHEMBL5707, mapped to UniProt Q9HAS3. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Solute carrier family 28 member 3
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL5707
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9HAS3
Solute carrier family 28 member 3
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Solute carrier family 28 member 3 is the right protein anchor across sources, using UniProt Q9HAS3 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSolute carrier family 28 member 3
UniProt AccessionQ9HAS3
Component TypeProtein
Sequence Length691 aa

Solute carrier family 28 member 3

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Solute carrier family 28 member 3, mapped to UniProt Q9HAS3. Sequence length is 691 aa.

Mapped IDQ9HAS3
Review nameSolute carrier family 28 member 3
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

2
Approved
2
Phase III
Assay Mix

Activity Type Distribution

IC503.0
KI23.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL477 5.68 Ki 2100.0 Approved
CHEMBL482331 5.54 Ki 2880.0 Preclinical
CHEMBL477 5.48 IC50 3300.0 Approved
CHEMBL100259 5.47 Ki 3400.0 Clinical
CHEMBL100259 5.27 IC50 5400.0 Clinical
CHEMBL516247 4.91 Ki 12350.0 Preclinical
CHEMBL516204 4.91 Ki 12400.0 Preclinical
CHEMBL245067 4.8 Ki 16000.0 Preclinical
CHEMBL474611 4.52 Ki 30020.0 Preclinical
CHEMBL482066 4.51 Ki 30770.0 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
2
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3
Total Assays
10
Tested Compounds
2
Assay Types
ADME — 2 assays, 3 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 3 5.5
cell-based format 1 0
Binding — 1 assays, 10 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 10 4.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine