Compound Detail
CHEMBL482939
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL482939 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FHSWWFYSXOSTCT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
331.4
MW (Da)
3.23
ALogP
4
HBA
1
HBD
55.4
PSA (Ų)
0.87
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.71
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | Ki | 7.71 | 7.71 | 19.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 | Ki | = | 19.6 | nM | 7.71 | Displacement of [3H]LSD from human recombinant 5HT6 receptor | 19346128 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19346128 | 10.1016/j.bmcl.2009.03.077 | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine