Compound Detail
CHEMBL484955
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Basic Information
| ChEMBL ID | CHEMBL484955 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UXJYMPRXLVIVCK-ATRFCDNQSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
304.2
MW (Da)
-0.65
ALogP
8
HBA
3
HBD
159.4
PSA (Ų)
0.38
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 7.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 7.18 | 7.18 | 66.0 | 1 |
| Respiratory syncytial virus CHEMBL612679 | EC50 | 6.12 | 6.12 | 750.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 66.0 | nM | 7.18 | Antiviral activity against HCV 1b infected in human 2209-23 cells by replicon as... | 19341305 |
| Respiratory syncytial virus | EC50 | = | 750.0 | nM | 6.12 | Antiviral activity against Respiratory syncytial virus subgenomic replicon syste... | 25667954 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19341305 | 10.1021/jm801595c | ADMET | 2 |
| 19341305 | 10.1021/jm801595c | Hepatitis C virus | 1 |
| 25667954 | 10.1021/jm5017279 | HeLa | 1 |
| 25667954 | 10.1021/jm5017279 | Respiratory syncytial virus | 1 |
Data from ChEMBL 36 via Core Engine