Compound Detail
CHEMBL485197
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Basic Information
| ChEMBL ID | CHEMBL485197 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LIBNBUULGCFJNR-QZTJIDSGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
311.5
MW (Da)
4.72
ALogP
2
HBA
2
HBD
49.3
PSA (Ų)
0.43
QED
0
Ro5 Violations
15
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 CHEMBL4794 | EC50 | 7.4 | 7.4 | 40.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | EC50 | = | 40.0 | nM | 7.4 | Agonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed a... | 19361197 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19361197 | 10.1021/jm900130m | Transient receptor potential cation channel subfamily V member 1 | 1 |
| 19361197 | 10.1021/jm900130m | Cannabinoid receptor 1 | 1 |
| 19361197 | 10.1021/jm900130m | Cannabinoid receptor 2 | 1 |
Data from ChEMBL 36 via Core Engine