Compound Detail
CHEMBL4855079
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Basic Information
| ChEMBL ID | CHEMBL4855079 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHAHMNSIYNZMNL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
313.4
MW (Da)
3.10
ALogP
6
HBA
1
HBD
68.1
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proteinase-activated receptor 4 CHEMBL4879420 | IC50 | 5.5 | 5.5 | 3130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proteinase-activated receptor 4 | IC50 | = | 3130.0 | nM | 5.5 | Antagonist activity at PAR4 in ICR mouse platelet-rich plasma assessed as inhibi... | 34391031 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34391031 | 10.1016/j.ejmech.2021.113764 | Proteinase-activated receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine