Proteinase-activated receptor 4 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt O88634. Use UniProt O88634 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O88634 as the stable identity anchor, then attach disease evidence before program review.
Proteinase-activated receptor 4
Review this target as Proteinase-activated receptor 4, mapped to UniProt O88634. Sequence length is 396 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proteinase-activated receptor 4 as ChEMBL target CHEMBL4879420, mapped to UniProt O88634. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Proteinase-activated receptor 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | O88634 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proteinase-activated receptor 4 |
| UniProt Accession | O88634 |
| Component Type | Protein |
| Sequence Length | 396 aa |
Proteinase-activated receptor 4
Review this target as Proteinase-activated receptor 4, mapped to UniProt O88634. Sequence length is 396 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4860533 | 7.08 | IC50 | 84.0 | Preclinical |
| CHEMBL4866566 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL4849569 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL4855875 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL4855377 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL4870185 | 6.19 | IC50 | 650.0 | Preclinical |
| CHEMBL4857938 | 6.1 | IC50 | 790.0 | Preclinical |
| CHEMBL4871001 | 6.08 | IC50 | 830.0 | Preclinical |
| CHEMBL3728507 | 6.03 | IC50 | 940.0 | Preclinical |
| CHEMBL4849478 | 6.02 | IC50 | 950.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-free format | 3 | 58 | 5.6 |